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Gonçalo Bernardes
Gonçalo
Bernardes
Group Leader
University of Cambridge, UK & Instituto de Medicina Molecular, Lisbon
Cambridge
United Kingdom
Portugal

EMBO LTF

2010
Institute of Pharmaceutical Sciences
Department of Chemistry and Applied Biosciences, ETH Zürich
Zürich
Switzerland
Research Interests
Proteins and Biochemistry
Chemical Site-selective Protein Modification; Synthetic Proteins; Carbohydrate Chemistry; Cancer Research
“Developing Drug Molecules for Therapy with Carbon Monoxide”
Romão, C.C.; Seixas, J.D.; Blättler, W.A.; Bernardes, G.J.L.*
Chem. Soc. Rev. 2012, 41, 3571.
* Corresponding author
“A Traceless Vascular Targeting Antibody-Drug Conjugate for Cancer Therapy”
Bernardes, G.J.L.; Casi, G.; Trüssel, S.; Hartmann, I.; Schwager, K.; Scheuermann, J.; Neri, D.
Angew. Chem. Int. Ed. 2012, 51, 941-944.
Selected as a Very Important Paper (VIP).
Article highlighted in Chimia, 2012, issue 3; ETH Life – “Starving Cancer”,
“A “Tag-and-Modify” Approach to Site-selective Protein Modification”
Chalker, J.M.; Bernardes, G.J.L.; Davis, B.G.
Acc. Chem. Res. 2011, 44, 730-741.
“CORM-3 Reactivity Towards Proteins: The Crystal Structure of a Ru(II) Dicarbonyl-Lysosyme Complex”
Santos-Silva, T.; Mukhopadkyay, A.; Seixas, J.D.; Bernardes, G.J.L.*; Romão, C.R.; Romão, M.J.
J. Am. Chem. Soc. 2011, 133, 1192-1195.
*Corresponding author
“Facile Conversion of Cysteine and AlkylCysteines to Dehydroalanine: Versatile and Switchable Access to Functionalized Proteins”.
Bernardes, G.J.L.; Chalker, J.M.; Errey, J.C.; Davis, B.G.
J. Am. Chem. Soc. 2008, 130, 5052-5053.
Article highlighted in Nature Chemical Biology, 2008, 4, 527-528; Chemical&Engineering News, March 31, 2008; Chemistry World, 2008, 5, 20; Chem. Commun. 2008, 6441.

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