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John Patrick Alao
John Patrick
Alao
Researcher
University of Gothenburg
Cell and Molecular Biology
Gothenburg
Sweden
www.molbio.gu.se
Germany

EMBO LTF

2006
Gothenburg University
Cell and Molecular Biology
Gothenburg
Sweden
www.molbio.gu.se
Research Interests
Molecular Medicine
Interactions between the DNA damage and stress response pathways in Fission yeast.
Molecular pharmacology of small molecule inhibitors with anti-cancer activity.
J. Leyton, J. P. Alao, M. Da Costa, et al.,(2006) In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3�- deoxy- 3�- [16 F] fluorothymidine positron emission tomography. Cancer Research 16885362
J. P. Alao, S. C. Gamble, A. V. Stavropoulou, et al., (2006) The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines. Molecular Cancer 16503970
J. P. Alao, A. V. Stavropoulou, E. W.-F. Lam, et al., (2006) Histone deacetylase inhibitor, Trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells. Molecular Cancer 16504004
R. Varshochi, F. Halim, A. Sunters, J. P. Alao, et al., (2005) ICI182,780 induces p21waf1 gene transcription through releasing HDAC1 and ER
J. P. Alao, E. W. Lam, S. Ali, et al., (2004) Trichostatin A inhibits breast cancer cell proliferation through estrogen receptor dependent transcriptional repression and estrogen receptor independent proteasomal degradation of cyclin D1. Clinical Cancer R

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